THE SІGNІFІCANCE OF CHANGES ІN PRІMARY HEMOSTASІS DURІNG ABDOMІNAL SEPSІS AS A POSSІBLE MECHANІSM OF SPІKE FORMATІON

Summary. Introduction. Abdominal sepsis (AS) is the most serious complication of inflammatory processes in abdominal cavity, characterized by high mortality and morbidity. Violation hemostasis one key components pathogenesis sepsis.
 Goal. Establishing pattern violations system thrombocyte-vascular patients with postoperative period, as a prerequisite for occurrence adhesions.
 Materials methods. The study covers observation 52 various forms AS, aged 18-69 years (41.93±3.47). control group consisted 17 who underwent planned surgical interventions not related to peritoneal cavity. dynamics content soluble fibrin-monomer complexes, prostacyclin thromboxane were determined their stable metabolites blood.
 Results discussion. Probable correlative dependences between complexes blood concentration TxB2 (positive correlation) level plasma (negative relationship) revealed. Identified primary AS indicate need active correction changes thromboxane-prostacyclin systems order prevent thrombotic complications septic nature.
 Conclusions. already on first day after surgery nature. Taking into account risk adhesion formation due peritoneum, it advisable consider identified factor disease.